AGARWAL LAB
  • Home
  • Science
  • Team
  • Publications
  • Contact
  • Home
  • Science
  • Team
  • Publications
  • Contact
Picture
The effect of light intensity, spectrum, and photoperiod on the physiological performance of Asparagopsis taxiformis tetrasporophytes
Dishon G, Resetartis HM, Tsai B, Jones AL, Agarwal V​, Smith JE
Algal Res 2023 76:103304
PDF

Picture
Pseudobulbiferamides: plasmid-encoded ureidopeptide natural products with biosynthetic gene clusters shared among marine bacteria of different genera
Zhong W, Aiosa NM, Deutsch JM, Garg N, Agarwal V​
J Nat Prod 2023 86(10):2414–2420
PDF

Picture
A leader-guided substrate tolerant RiPP brominase allows Suzuki–Miyaura cross-coupling reactions for peptides and proteins​
​Nguyet NA, Agarwal V​
Biochemistry 2023 62(12), 1838–1843.
​PDF

Picture
Discovery and biosynthesis of ureidopeptide natural products macrocyclized via indole N-acylation produced by marine Microbulbifer spp. bacteria
​Zhong W, Deutsch JM, Yi D, Abrahamse NH, Mohanty I, Moore SG, McShan AC, Garg N, Agarwal V​
ChemBioChem 2023 e202300190​.
ChemBioTalents 2022/23 special issue. 
PDF

Picture
Biosynthesis-guided discovery and engineering of α-pyrone natural products from type I polyketide synthases
​Yi D, Agarwal V
ACS Chem Biol 2023 18(5), 1060–1065​.
PDF

Picture
Limited metabolomic overlap between commensal bacteria and marine sponge holobionts revealed by large scale culturing and mass spectrometry-based metabolomics: an undergraduate laboratory pedagogical effort at Georgia Tech 
​Deutsch JM, Green MP, Akavaram P, Davis AC, Diskalkar SS, Du Plessis IA, Fallon HA, Grason EM, Kauf EG, Kim ZM, Miller II JR, Neal AL, Riera T, Stroeva S-E, Tran J, Tran V, Coronado AV, Coronado VV, Wall BT, Yang C, Mohanty I, Abrahamse NH, Freeman CJ, Easson CG, Fiore CL, Onstine AE, Djeddar N, Biliya S, Bryksin AV, Garg N, Agarwal V
Marine Drugs 2023 21(1), 53.
PDF

Picture
A silent biosynthetic gene cluster from a methanotrophic bacterium potentiates discovery of a substrate promiscuous proteusin cyclodehydratase
​Nguyet NA, Cong Y, Hurrell RC, Arias N, Garg N, Puri AW, Schmidt EW, Agarwal V
ACS Chem Biol 2022 17(6), 1577–1585​.
PDF

Picture
A nonfunctional halogenase masquerades as an aromatizing dehydratase in biosynthesis of pyrrolic polyketides by type I polyketide synthases 
​Yi D, Niroula D, Gutekunst WR, Loper JE, Yan Q, Agarwal V*
ACS Chem Biol 2022 17(6), 1351–1356​.
PDF

Picture
Resolving the hydride transfer pathway in oxidative conversion of proline to pyrrole
​Acharya A, Yi D, Pavlova A, Agarwal V*, Gumbart JC*
Biochemistry 2022 61, 206–215.
PDF

Picture
Hepatic demethylation of methoxy-bromodiphenyl ethers and conjugation of the resulting hydroxy-bromodiphenyl ethers in a marine fish, the red snapper, Lutjanus campechanus, and a freshwater fish, the channel catfish, Ictalurus punctatus
Sultana A, Hindrichs C, Cisneros KV, Weaver CJ, Faux LR, Agarwal V, James MO​
Chemosphere. 2022 286, 131620.
PDF

Picture
An obligate peptidyl brominase underlies the discovery of highly distributed biosynthetic gene clusters in marine sponge microbiomes
Nguyen NA, Lin Z, Mohanty I, Garg N, Schmidt EW, Agarwal V
JACS. 2021 143, 10221–10231
PDF

Picture
​Gatekeeping ketosynthases dictate initiation of assembly line biosynthesis of pyrrolic polyketides
Yi D, Acharya A, Gumbart JC, Gutekunst WR, Agarwal V
JACS. 2021 143, 7617−7622
PDF

Picture
Enzymatic synthesis assisted discovery of proline-rich macrocyclic peptides in marine sponges
​Mohanty I,* Nguyen NA,* Moore SG, Biggs JS, Gaul DA, Garg N, Agarwal V
ChemBioChem 2021 22, 2614–2618
*co-first authors
PDF

Picture
Presence of bromotyrosine alkaloids in marine sponges is independent of metabolomic and microbiome architectures
​Mohanty I, Tapadar S, Moore SR, Biggs JS, Freeman CJ, Gaul DA, Garg N, Agarwal V
mSystems. 2021 6(2):e01387–20​
PDF

Picture
Stereochemical assignment and absolute abundance of non-proteinogenic amino acid homoarginine in marine sponges​
​Mohanty I, Moore SG, Biggs JS, Freeman CJ, Gaul DA, Garg N, Agarwal V
ACS Omega 2021 6, 33200–33205.
PDF

Picture
Obligate brominating enzymes underlie bromoform production by marine cyanobacteria
Thapa HR, Agarwal V
J Phycol. 2021 
57, 1131–1139​
PDF

Picture
Precursor-guided mining of marine sponge metabolomes lends insight into biosynthesis of pyrrole-imidazole alkaloids
Mohanty I, Moore SG, Yi D, Biggs JS, Gaul DA, Garg N, Agarwal V
ACS Chem Biol. 2020 15(8), 2185–2194
​PDF

Picture
Genetic and biochemical reconstruction of bromoform biosynthesis in Asparagopsis lends insights in seaweed ROS enzymology
 Thapa HR, Lin Z, Yi D, Smith JW, Schmidt EW, Agarwal V
ACS Chem Biol. 2020 15(6), 1662–1670

​PDF

Picture
Multi-omic profiling of Melophlus sponges reveals diverse metabolomic and microbiome architectures that are non-overlapping with ecological neighbors
Mohanty I, Podell S, Biggs JS, Garg N, Allen EE, Agarwal V
Mar Drugs. 2020 18(2), 124
​PDF

Picture
Insights into thiotemplated pyrrole biosynthesis gained by crystal structure of flavin-dependent oxidase in complex with carrier protein
​Thapa HR, Robbins JM, Moore BS, Agarwal V
Biochemistry. 2019 58(7):918–929.
PDF

Picture
Chemical ecology of marine sponges: new opportunities through "-omics".
Paul VJ, Freeman CJ, Agarwal V
Integr Comp Biol. 2019 

​PDF

Picture
Mass spectrometry-based integration and expansion of the chemical diversity harbored within a marine sponge
Cantrell TP, Freeman CJ, Paul VJ, Agarwal V*, Garg N*
J Am Soc Mass Spectrom. 2019 30(8):1373–1384
​*corresponding

​PDF

Picture
Sulfonation and glucuronidation of hydroxylated bromodiphenyl ethers in human liver
​Cisneros KV, Agarwal V, James MO
Chemospehere. 2019 226:132–139.
PDF

Picture
Chemoenzymatic synthesis of starting materials and characterization of halogenases requiring acyl carrier protein-tethered substrates.
​Thapa HR, Lail AL, Garg N, Agarwal V
Methods Enzymol. 2018 604:333–366.
PDF

Picture
Assaying Oxidative Coupling Activity of CYP450 Enzymes
Agarwal V
Methods Enzymol. 2018 604:499–521.

  • Home
  • Science
  • Team
  • Publications
  • Contact