An obligate peptidyl brominase underlies the discovery of highly distributed biosynthetic gene clusters in marine sponge microbiomes
Nguyen NA, Lin Z, Mohanty I, Garg N, Schmidt EW, Agarwal V
JACS. 2021 Accepted, in press.
Nguyen NA, Lin Z, Mohanty I, Garg N, Schmidt EW, Agarwal V
JACS. 2021 Accepted, in press.
Gatekeeping ketosynthases dictate initiation of assembly line biosynthesis of pyrrolic polyketides
Yi D, Acharya A, Gumbart JC, Gutekunst WR, Agarwal V
JACS. 2021 143, 7617−7622
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Yi D, Acharya A, Gumbart JC, Gutekunst WR, Agarwal V
JACS. 2021 143, 7617−7622
Obligate brominating enzymes underlie bromoform production by marine cyanobacteria
Thapa HR, Agarwal V
J Phycol. 2021 accepted, in press
PDF
Thapa HR, Agarwal V
J Phycol. 2021 accepted, in press
Presence of bromotyrosine alkaloids in marine sponges is independent of metabolomic and microbiome architectures
Mohanty I, Tapadar S, Moore SR, Biggs JS, Freeman CJ, Gaul DA, Garg N, Agarwal V
mSystems. 2021 6(2):e01387-20
PDF
Mohanty I, Tapadar S, Moore SR, Biggs JS, Freeman CJ, Gaul DA, Garg N, Agarwal V
mSystems. 2021 6(2):e01387-20
Precursor-guided mining of marine sponge metabolomes lends insight into biosynthesis of pyrrole-imidazole alkaloids
Mohanty I, Moore SG, Yi D, Biggs JS, Gaul DA, Garg N, Agarwal V
ACS Chem Biol. 2020 15(8), 2185-2194
PDF
Mohanty I, Moore SG, Yi D, Biggs JS, Gaul DA, Garg N, Agarwal V
ACS Chem Biol. 2020 15(8), 2185-2194
Genetic and biochemical reconstruction of bromoform biosynthesis in Asparagopsis lends insights in seaweed ROS enzymology
Thapa HR, Lin Z, Yi D, Smith JW, Schmidt EW, Agarwal V
ACS Chem Biol. 2020 15(6), 1662-1670
PDF
Thapa HR, Lin Z, Yi D, Smith JW, Schmidt EW, Agarwal V
ACS Chem Biol. 2020 15(6), 1662-1670
Multi-omic profiling of Melophlus sponges reveals diverse metabolomic and microbiome architectures that are non-overlapping with ecological neighbors
Mohanty I, Podell S, Biggs JS, Garg N, Allen EE, Agarwal V
Mar Drugs. 2020 18(2), 124
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Mohanty I, Podell S, Biggs JS, Garg N, Allen EE, Agarwal V
Mar Drugs. 2020 18(2), 124
Mass spectrometry-based integration and expansion of the chemical diversity harbored within a marine sponge
Cantrell TP, Freeman CJ, Paul VJ, Agarwal V*, Garg N*
J Am Soc Mass Spectrom. 2019 30(8):1373-1384
*corresponding
PDF
Cantrell TP, Freeman CJ, Paul VJ, Agarwal V*, Garg N*
J Am Soc Mass Spectrom. 2019 30(8):1373-1384
*corresponding
Chemical ecology of marine sponges: new opportunities through "-omics".
Paul VJ, Freeman CJ, Agarwal V
Integr Comp Biol. 2019
PDF
Paul VJ, Freeman CJ, Agarwal V
Integr Comp Biol. 2019
Insights into thiotemplated pyrrole biosynthesis gained by crystal structure of flavin-dependent oxidase in complex with carrier protein
Thapa HR, Robbins JM, Moore BS, Agarwal V
Biochemistry. 2019 58(7):918-929.
PDF
Thapa HR, Robbins JM, Moore BS, Agarwal V
Biochemistry. 2019 58(7):918-929.
Sulfonation and glucuronidation of hydroxylated bromodiphenyl ethers in human liver
Cisneros KV, Agarwal V, James MO
Chemospehere. 2019 226:132-139.
Cisneros KV, Agarwal V, James MO
Chemospehere. 2019 226:132-139.
Chemoenzymatic Synthesis of Starting Materials and Characterization of Halogenases Requiring Acyl Carrier Protein-Tethered Substrates.
Thapa HR, Lail AL, Garg N, Agarwal V
Methods Enzymol. 2018 604:333-366.
Thapa HR, Lail AL, Garg N, Agarwal V
Methods Enzymol. 2018 604:333-366.
